Molecular modification of ZnO surface

Abstract

Toward the fabrication of biosensing medical devices with enzyme-modified field effect transistors based on zinc oxide (ZnO), surface modifications using organic molecules were employed. In case of molecules containing thiol groups, it was found that molecules on ZnO surfaces were desorbed during water immersion, while ZnO surfaces modified by a silane-coupling agent were stable in water. Glucoseoxidase (GOX), an enzyme, specifically reacting with glucose, could be immobilized on molecular modified ZnO surfaces.