Chemical Constituents of Euphorbia marschalliana Boiss

Abstract

Acetone extract of aerial parts of Euphorbia marschalliana collected from Iran has been subjected to different chromatography techniques for fractionation and purification. The stereo-structures of the myrsinol esters 15-O-acetyl-3-O-propionyl-5-O-butanoyl-7-O-nicotinoylmyrsinol (1) and 15-O-acetyl-3,5-O-dibutanoyl-7-O-nicotinoylmyrsinol (2) have been probed using ROESY spectroscopy and modified for the stereochemistry at C-6, C-12 and C-13. β-Sitosterol (3), 29-norcycloart-5-ene (4), 5,8-lanostadiene-3β-ol (5), 3β,24(S),25-trihydroxycycloartane (6), 3β,24(R),25- trihydroxycycloartane (7) and 24-methylenecycloartan-3β-ol (8) were identified for the first time in this plant.