Identification of hemoglobins and hemoglobinopathies by electrophoresis on cellulose acetate plates impregnated with citrate agar

Abstract

The authors describe a method of electrophoresis of hemoglobin on cellulose acetate plates impregnated with citrate agar, which remain stable for many months and are used to confirm rapidly the presence of hemoglobins S and C and the hemoglobinopathies associated with them. The method also provides excellent separations of hemoglobins F and A and reliable identification of genetically determined hemoglobin abnormalities in the newborn.