Influence of Trehalose Mouth Rinse on Anaerobic and Aerobic Exercise Performance

Abstract

Trehalose is a disaccharide consisting of 2 glucose units linked in an alpha 1,1-glycosidic bond. Pre-exercise trehalose ingestion enhances exercise performance within 30 minutes. Enhanced performance was hypothesized to be due to a mouth rinse effect. A 3-arm double-blind crossover trial was conducted to test this hypothesis. Ten healthy male collegiate distance runners rinsed their mouths with either trehalose (6% w/v) or maltose (6% w/v) or acesulfame potassium (0.04 mg/mL) for 5 seconds and then performed an exercise assessment composed of 6-second peak power and endurance tests. Trehalose induced the highest mean power output (P