Prevalencia de anticuerpos IgG al toxoide tetánico en trabajadores sanitarios

Abstract

In 2009 the Ministry of Health of Spain published a new guide for the vaccination of diphtheria and tetanus. There are discrepancies with the time of inoculation of the booster with other countries and medical societies. The objective of this study was to estimate the health worker prevanlencia antibody negative to tetanus toxoid and see to it associated factors. Material and Methods: A descriptive study. The variables analyzed were: IgG - Tetanus Toxin, time last dose of vaccination, total dose, age, sex, hospital, smoking history and body mass index. Logistic regression model was constructed. In order to identify areas of more sensitive and specific cut for temporary variables (time since last dose and age) ROC curves were calculated. Results: The variables, age O.R= 17,56 (1,840 - 167,760), inoculated vaccine doses to workers O.R= 0,064 (0,006 - 0,908) and the time of the last dose of vaccination O.R= 1,03 (1,017 - 1,047) are significant variables in the multivariate analysis. The cut-off points for age is 54 years (Sensitivity S= 0,72, Specificity SP=0,77) and 15 years after the last dose (S= 0,88, SP =0,86), above this cut the likelihood of having antibodies to tetanus is high. Conclusions: In a worker or documents referred to more than 15 years ago the last dose revaccination should ask, if this worker also reported not having more than 5 inoculated dose and has over 54 years would be highly recommended revaccination.