P2510Left ventricular function in relation to chronic residential air pollution in a general population

Abstract

Background: In view of increasing heart failure (HF) epidemic, identification of the environmental trigger of left ventricular (LV) dysfunction is of paramount importance. Purpose(s): We investigated the association between LV function and air pollutants in a general population. Method(s): In 671 randomly recruited Flemish (51.7% women; mean age, 50.4 years), we echocardiographically assessed systolic regional LV strain and strain rate and diastolic function. Result(s): Annual individual residential exposures to black carbon (BC), PM2.5, PM10 and NO2 averaged 1.19, 13.0, 17.7, and 16.8 mug/m3. After mutli-variable adjustment, regional systolic LV function decreased (P