Minimal change nephropathy associated with anaplastic carcinoma of bronchus

Abstract

Nephrotic syndrome associated with extra-renal malignancy shows a characteristic pattern: carcinoma is most frequently associated with membranous glomerulonephritis and Hodgkin's disease with minimal change nephropathy. We report a patient with minimal change nephropathy in association with anaplastic carcinoma of the bronchus. Strong temporal evidence of a causal relationship is presented. The dissociation in the response of the two conditions to treatment of the tumour after relapse may be evidence of an indirect pathogenesis. © The Fellowship of Postgraduate Medicine, 1986.