Phytochemical Screening of Moringa oleifera as Antioxidant and Anticancer through Chemoinformatics Approach

Abstract

Moringa oleifera, also known as kelor, this plant is better known to have benefits in the field of health including having properties as an antioxidant and anticancer. Several previous studies have revealed the potential of Moringa oleifera in the health sector such as anti-inflammatory, wound healing, antidiabetic, and antiviral. This study aims to obtain preliminary information on the possible bioactive activities of Moringa oleifera, which can be the basis for further research and development of its therapeutic potential. The in silico method used in this study consists of sample preparation of compounds from Moringa oleifera in the database, prediction of antioxidant and anticancer probabilities, and visualization of the three-dimensional structure of target compounds with positive predictions. Moringa oleifera has Rutin compounds that act as antioxidants and anticancer based on bioactivity tests. This can provide an illustration of future prospects that Moringa oleifera can be used as an alternative treatment and supplement. The higher probability of activity indicates the potential presence that results when these compounds are already used in the form of standardized drug products.