Mathematical representation of solubility of electrolytes in binary solvent mixtures using Jouyban-Acree model

Abstract

Applicability of a solution model for calculating salt's solubility in binary solvent mixtures was shown. The accuracy of the proposed model was evaluated by computing mean percentage deviation (MPD) employing available solubility data of electrolytes in binary solvents at various temperatures from the literature. The overall MPD (±S.D.) for correlation of solubility data was 4.7±5.1% and for prediction using model trained by a minimum number of experimental data points was 10.5±12.5%. © 2005 Pharmaceutical Society of Japan.