Sesquiterpenoids and xanthones from the kiwifruit-associated fungus bipolaris sp. And their anti-pathogenic microorganism activity

Abstract

Nine previously undescribed sesquiterpenoids, bipolarisorokins A–I (1–9); two new xan-thones, bipolarithones A and B (10 and 11); two novel sativene-xanthone adducts, bipolarithones C and D (12 and 13); as well as five known compounds (14–18) were characterized from the kiwifruit-associated fungus Bipolaris sp. Their structures were elucidated by extensive spectroscopic methods, electronic circular dichroism (ECD),13 C NMR calculations, DP4+ probability analyses, and single crystal X-ray diffractions. Many compounds exhibited anti-pathogenic microorganism activity against the bacterium Pseudomonas syringae pv. actinidiae and four pathogenic microorganisms.