Photoaging: Reversal of the Oxidative Stress Through Dietary Changes and Plant-Based Products

  • Hooda R
  • Madke B
  • Choudhary A
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Abstract

Redox flagging represents all life processes, and maintaining a physiological level of antioxidants is essential for the legitimate working of the cell. Genetics and environmental triggers are two major culminating factors for skin aging, both chronological and photoaging. The latter, however, relies principally upon the level of ultraviolet radiation (UVR) exposure and the skin phototype. Apart from causing DNA damage, UVR also stimulates the receptors present in keratinocytes as well as fibroblasts. This in turn leads to the breakdown of collagen and a breach in the generation of new collagen. It is speculated that the breakdown of collagen in the dermis is ensured by the defective restoration that ultimately hampers the structural integrity of skin, leading to wrinkled and atrophic skin. The skin has an admixture of various endogenous antioxidants that work synergistically with vitamins and minerals to maintain cellular equilibrium. Although, their role in safeguarding the cells against the detrimental effects induced by UVR is still questionable and requires further research. However, the advancement in the biology of skin has led to the development of strategies that aim at skin rejuvenation and retarding the progression of photoaging and its visible signs. Photoaging in this article is reviewed in light of current concepts in pathogenesis and its prevention. In addition, the article focuses on both prevailing and forthcoming treatment strategies primarily through plant-based products that will help slow down the process of photoaging.

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Hooda, R., Madke, B., & Choudhary, A. (2023). Photoaging: Reversal of the Oxidative Stress Through Dietary Changes and Plant-Based Products. Cureus. https://doi.org/10.7759/cureus.37321

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