Segmental expression of the T-box transcription factor, Tbx2, during early somitogenesis

Abstract

Tbx2 belongs to the T-box transcription factor gene family and is expressed in a variety of tissues and structures throughout development, although not all expression domains have been thoroughly described. Two areas of segmented expression along the rostral-caudal axis of E10.5-11.5 embryos were identified as inter-somitic vessels and dorsal root ganglia. In addition, Tbx2 expression is observed during somitogenesis beginning at E9.5, both in the posterior half of prospective somites and in a progressively restricted pattern in recently formed somites. © 2006 Wiley-Liss, Inc.