Access to 6-hydroxy indolizines and related imidazo[1,5-a]pyridines through the SN2 substitution/condensation/tautomerization cascade process

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Abstract

A simple and efficient cascade reaction was developed for the construction of hydroxy substituted indolizines from pyrrole-2-carbaldehydes and commercially available 4-halogenated acetoacetic esters. Their optical properties were also evaluated.

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Duan, G., Liu, H., Zhang, L., Yuan, C., Li, Y., & Ge, Y. (2021). Access to 6-hydroxy indolizines and related imidazo[1,5-a]pyridines through the SN2 substitution/condensation/tautomerization cascade process. RSC Advances, 11(41), 25624–25627. https://doi.org/10.1039/d1ra04425g

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