Abstract
Positively charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was observed for respiration-deficient mutants lacking genes encoding proteins associated with the mitochondrion. © 2013, American Society for Microbiology.
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CITATION STYLE
Smith, M. R., Boenzli, M. G., Hindagolla, V., Ding, J., Miller, J. M., Hutchison, J. E., … Bakalinsky, A. T. (2013). Identification of gold nanoparticle-resistant mutants of Saccharomyces cerevisiae suggests a role for respiratory metabolism in mediating toxicity. Applied and Environmental Microbiology, 79(2), 728–733. https://doi.org/10.1128/AEM.01737-12
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