Prediction of preeclampsia and fetal growth restriction by uterine artery Doppler evaluation

Abstract

Foetal growth restriction and preeclampsia are important causes of perinatal morbidity and mortality. Studies show a robust correlation between these issues and diffuse endothelial dysfunction. Pregnant women who show significant resistance to uteroplacental blood flow are more likely to develop preeclampsia, according to clinical research. Pregnancies with a higher risk of difficulties due to defective placentation can be predicted by uterine artery Doppler investigations, which can be performed in both the first and second trimesters. These studies had a false positive rate of 5% to 7% and a sensitivity of 80% to 90% in predicting severe preeclampsia. When done between 20 and 24 weeks of gestation, uterine artery Doppler screening is more effective than screening during the first trimester and satisfies all screening test requirements. To find out how well maternal blood indicators and uterine artery Doppler work together to predict unfavorable pregnancy outcomes, more research is required.