Synthesis Characterisation and anti-microbial properties of two Salicylaldimine Schiff base complexes of transition metals

Abstract

Schiff bases and their metal complexes are widely used in the area of pharmacology owing to their anti-microbial properties. In this article, we detail the synthesis of two metal complexes, viz. Cu(II) and Zn(II) complexes of a salicylaldimine Schiff base formed from orthophenylene diamine (o-phdn) and salicylaldehyde. The complexes 1 [Cu(sal-o-phdn)] and 2 [Zn(sal-o-phdn)] are characterized by spectroscopic techniques like Fourier Transform Infrared spectroscopy (FT IR) and UV-Visible spectroscopic studies. The biological activity of the two complexes along with the Schiff base resistant to two gram positive and two gram negative bacteria is measured by Disc diffusion method. The complexes are found to be good candidates against certain microorganisms.