Experimental study on physical exercise in diabetes: pathophysiology and therapeutic effects

Abstract

Diabetes is a chronic disease potentially disabling. The purpose of the study was to investigate the effects of exercise in type II diabetes in obese subjects, both active and sedentary. The study demonstrates how exercise can be a useful approach to reducing blood glucose levels. In addition, we monitored changes in some hematochemical parameters at the end of the intervention. We recruited 90 people aged 35 to 40 years, both males and females. All were type II diabetics and were randomly randomized into group A (n=50, sedentary) and group B (n=40, active). Anthropometric parameters (BMI) and some hematochemical values (blood glucose, cholesterol, Hb1Ac) were assessed. At the end of the intervention, blood glucose values decreased from 160/150 (mg/dl) to 130 (mg/dl) in group A, and in group B from 140 (mg/dl) to 120/110 (mg/dl). BMI decreased by 60% in both groups, with greater significance in group B, of which 60% were obese. The training protocol used demonstrated that exercise combined with insulin therapy regulates blood glucose levels in obese and non-obese diabetics.