Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids

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Abstract

How is the cochlear clock regulated? Cederroth, Park et al. show that circadian rhythms in the cochlea are controlled by the suprachiasmatic nucleus and glucocorticoids from the adrenal glands that act as major regulators of the differential sensitivity to day and night noise trauma.

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Cederroth, C. R., Park, J. sub, Basinou, V., Weger, B. D., Tserga, E., Sarlus, H., … Canlon, B. (2019). Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids. Current Biology, 29(15), 2477-2487.e6. https://doi.org/10.1016/j.cub.2019.06.057

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