Abstract
Glycopyrrolate, a quaternary ammonium anticholinergic compound, and atropine were evaluated in combination with neostigmine for antagonism of non-depolarizing neuromuscular block. A total of 641 patients were investigated in a "true-to-life" situation. The patients receiving glycopyrrolate with neostigmine had smaller changes in heart rate than those who received atropine. This was particularly apparent in patients with cardiovascular disease. © 1980 Macmillan Publishers Ltd.
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CITATION STYLE
Cozanitis, D. A., Dundee, J. W., Merrett, J. D., Jones, C. J., & Mirakhur, R. K. (1980). Evaluation of glycopyrrolate and atropine as adjuncts to reversal of non-depolarizing neuromuscular blocking agents in a “true-to-life” situation. British Journal of Anaesthesia, 52(1), 85–89. https://doi.org/10.1093/bja/52.1.85
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