The correlation of high-density lipoprotein (Hdl) with adiponectin levels among obese adolescents in denpasar, bali, indonesia

Abstract

Background: Obesity is a state of Body Mass Index (BMI) above or equal to 25 kg/m2. In obesity, dyslipidaemia can occur alone or together with other comorbid. This situation could affect proinflammatory and anti-inflammatory cytokines that lead to health problems. Several parameters assessed in dyslipidaemia conditions include High-Density Lipoprotein (HDL) and adiponectin. This study aims to evaluate the correlation between HDL and adiponectin levels in obese adolescents. Methods: A cross-sectional observational study was conducted among 33 obese adolescence (0-18 years) who met the inclusion criteria at Junior and Senior High School in Denpasar during August 2018-January 2019 period. Variables evaluated in this study were age, sex, weight, height, BMI, HDL, and adiponectin. The correlation assessment of HDL and adiponectin levels was conducted by Partial Correlation test after controlling age and sex using SPSS version 23 for Windows. Results: Males (66.70%) were predominant than females (33.30%) with a ratio of 2: 1. The average age of respondents was 15.51± 0.70 years old. The mean body weight was 91.04±15.40 kilograms, followed by height (163.09±7.40 cm), BMI (34.08±3.90 kg/m2), HDL (43.40±8.00 mg/dl), and adiponectin (4.55±2.1 µg/ml). There was a very weak and not significant correlation by Partial correlation test (r=0.143; p=0.444) between HDL and adiponectin levels. Conclusion: Our study found There was a very weak and not significant correlation between HDL and adiponectin levels among obese adolescent in Denpasar, Bali, Indonesia.