Understanding the pathogen evolution and transmission prevention measures: Recent findings on molecular interventions towards covid-19 therapeutics via hints from the past

Abstract

The novel coronavirus pandemic has spread over in 150 countries as of March 2020. Approximately 900,000 people have been infected so far (WHO). Preventive measures are been taken globally to contain the rapid spread of virus. Compared to 2002 SARS epidemic, COVID-19 is apparently less lethal but far more contagious as it spreads more easily among individuals. This review highlights ongoing progress in figuring out the structure of major proteins designing vaccines and therapeutics to combat COVID-19 while also concen-trating on developing preventive steps to avoid the emerging infection of viruses.