Abstract
Recent findings demonstrate that dendritic cells in prostate tumors induce immune tolerance in tumor antigen-specific CD8(+) T cells. We propose that DC tolerogenicity can be regulated by expression of Foxo3; silencing Foxo3 expression enhances anti-tumor immune responses and renders FOXO3 a potential target for immunotherapy.
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CITATION STYLE
APA
Watkins, S. K., & Hurwitz, A. A. (2012). FOXO3. OncoImmunology, 1(2), 252–254. https://doi.org/10.4161/onci.1.2.18241
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