Resultados de callosotomía en adultos con diagnóstico de epilepsia refractaria y drop-attack

Abstract

Introduction: For patients with refractory epilepsy patients, the sub-group characterized for seizures involving falls or drop-attack, the technique of callosotomy, as a palliative measure has been validated and used to control this type of seizures. Method: Group of 16 patients operated during period of four years, evaluated by protocol, which was performed as a palliative callosotomy crisis management technique was evaluated. Results: The observed group, 10 were males and 6 females, mean age 30 years, range between 19-46 years. Average evolution of epilepsy in 20.8 years, 14 cases crisis was starting before age 14. Major crises were TCG (generalized tonic clonic) and a tonic seizures were being 62.5 percent daily and 37.5 percent monthly, 100 percent had a history of TEC (brain trauma) and 56 percent history of status epilepticus. Was performed anterior callosotomy two thirds in 8 patients (mean follow-up 23.8 months), 6 patients complete callosotomy (average follow-up 15.5 months), and in 2 cases, two anterior thirds and then total callosotomy (1 case 22 months, and another 1 month follow-up). Seizures management fall > 50 percent in 75 percent of patients (3 cases without seizures of fall with anterior callosotomy two thirds), and for complete callosotomy, 100 percent control crisis in > 80 percent of patients (3 cases without seizures of fall was found in this group). Conclusion: The technique callosotomy as a palliative measure in the context of drop-attack or crises involving falls, in our experience with adult patients, has been a good tool in controlling this type of seizures.