Synthesis, Spectroscopic and Thermal Characterization and Antioxidant Activities of Three Schiff Bases Derived from Aminophenol

Abstract

The main objective of this work is synthesized three Schiff bases: (E)-2(((2hydroxyphenyl)imino)methyl)-6-methoxyphenol (I), (E)-2-(((3-hydroxyphenyl) imino)-Methyl)-6-Methoxyphenol(II) and (e)-2-(((4-hydroxyphenyl)imino)methyl)-6amethoxyphenol(III) derivative of 2-hydroxy-3-methoxybenzaldehyde and ortho/meta / para-aminophenol, their structures were confirmed by spectroscopic methods: UV-Vis, FTIR, (1H, 13C NMR). Firstly, a thermogravimetric analysis (TGA/DTG) study of the composite Schiff bases proved them to be thermally stable. Secondly, the study of the biological properties of the synthesized compounds allowed the evaluation of the antioxidant activity by conventional methods (scavenging of the DPPH radical, and bleaching of ß-carotene). The results demonstrated a variable degree of inhibitory effects on the growth of synthesized Schiff bases.