Effect of bordetella pertussis adjuvant on parasite-specific ige response inparagonimus ohirai-infected rats

Abstract

Parasite-specific IgE response in rats infected with metacercariae of the lung fluke, Paragonimus ohirai, was enhanced about 8 times by Bordetella pertussis adjuvant. In rats infected by intraperitoneal transplantation of adult worms, the adjuvant markedly increased the usually low or absent parasite-specific IgE response. The most effective time of the adjuvant administration was different between the two modes of infections. © 1988 S. Karger AG, Basel.