Abstract
RNF2/RING1B is amplified and overexpressed in numerous tumors and contributes to tumorigenicity; however, the biologic importance is poorly understood. Surprisingly, the role of RNF2 in tumorigenesis and invasion can be separated into catalytically independent and catalytically dependent processes.
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CITATION STYLE
APA
Black, J. C., & Whetstine, J. R. (2015). RNF2 E3 or not to E3: Dual roles of RNF2 overexpression in melanoma. Cancer Discovery, 5(12), 1241–1243. https://doi.org/10.1158/2159-8290.CD-15-1285
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