The postoperative relief of vertigo and migraine in Meniere’s disease patients with and without migraine

Abstract

Background: The correlation of Meniere’s disease (MD) and migraine remains unclear. Objectives: To explore the relation of MD and migraine by analyzing the postoperative relief of vertigo and migraine in MD patients with migraine. Material and methods: 104 MD patients were enrolled. The monthly vertigo episodes (MVE) and migraine headache index (MHI) were used for assessing effectiveness at pre- and post-endolymphatic sac decompression (ELSD). First, patients were divided into MD with migraine and MD two groups with vertigo relief rates compared. Then, the postoperative relief of vertigo and migraine in MD patients with migraine was analyzed. Results: The postoperative vertigo relief rates for MD and MD with migraine groups were 46.7% and 40.68% with no significant difference. In MD patients with migraine, postoperative MVE and MHI decreased significantly. The Kappa value calculated for vertigo and migraine outcomes was 0.505. The absence of hypertension was independently predictive of relief of vertigo and migraine. The male was independently predictive for relief of migraine. Conclusions and significance: ELSD is effective for MD patients with migraine. The postoperative relief of vertigo and migraine has a certain consistency, suggesting MD and migraine may share some common pathogenesis which may be related to inflammation.