Coenzyme Q10deficiency in septic shock patients

Abstract

Donnino and colleagues provide new insights into the field of oxidative stress and mitochondrial dysfunction during septic shock. These authors suggest a coenzyme Q10(CoQ10) deficiency in patients with septic shock. Larger prospective observational trials measuring CoQ10in patients with septic shock are required to confirm the possibility of CoQ10depletion. This study is a new step toward a study testing CoQ10as a potential therapeutic agent for patients with septic shock. © 2011 BioMed Central Ltd.