Human leukocyte antigen and cytokine gene variants as predictors of recurrent Chlamydia trachomatis infection in high-risk adolescents

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Abstract

Antigen presentation and immune activation are essential to the effective control of infectious diseases. In 485 North American adolescents at high risk for genital Chlamydia trachomatis infection, we found 2 human leukocyte antigen variants (DRB1*03-DQB1*04 and DQB1*06) to be associated with recurrent Chlamydia infection (adjusted relative odds [RO], >2.0; P

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Wang, C., Tang, J., Geisler, W. M., Crowley-Nowick, P. A., Wilson, C. M., & Kaslow, R. A. (2005). Human leukocyte antigen and cytokine gene variants as predictors of recurrent Chlamydia trachomatis infection in high-risk adolescents. Journal of Infectious Diseases, 191(7), 1084–1092. https://doi.org/10.1086/428592

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