A new antibacterial polyketide from the endophytic fungi aspergillus fumigatiaffinis

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Abstract

A new antibacterial polyketide (-) palitantin was isolated from Aspergillus fumigatiaffnis, an endophytic fungi from a medicinal plant Tribulus terestris. The structure of the antibacterial metabolite was established using 1D and 2D NMR together with mass spectroscopy. (-) Palitantin was found to inhibit the growth of Enterococcus faecalis UW 2689 and Streptococcus pneumoniae with MIC value of 64µg/mL.

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Ola, A. R. B., Tawo, B. D., Belli, H. L. L., Proksch, P., Tommy, D., & Hakim, E. H. (2018). A new antibacterial polyketide from the endophytic fungi aspergillus fumigatiaffinis. Natural Product Communications, 13(12), 1573–1574. https://doi.org/10.1177/1934578x1801301202

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