TOTAL SYNTHESIS IN BRAZIL EMPLOYING PALlADIUM CROSS-COUPLING AS KEY STEP

Abstract

This article aims to show the selected total syntheses of organic compounds conducted by Brazilian researchers, performed in Brazil, which have employed a palladium catalyzed cross-coupling reaction as key step. We intended to thus create an account, although restricted to the use of palladium, showing the evolution and current state of art of Synthetic Organic Chemistry in Brazil, which has advanced and accept the challenge of total synthesis of increasingly complex molecules, registering growth and maturity of this area among Brazilian researchers.