Serum glucose and fructosamine levels as possible indicators of diabetes mellitus in dogs

Abstract

The aim of this study was to evaluate the usefulness of the measurement of glucose and serum fructosamine as possible indicative biomarkers for the diagnosis of canine diabetes mellitus (CDM). An analytical, descriptive, cross-sectional study was developed with a sample of 30 canines from a shelter in Cundinamarca, Colombia. The animals were without clinical signs of CDM. Data on sex, breed, age, diet, reproductive history, symptoms related to CDM and vaccination status of each animal were taken. A sample was collected from the cephalic vein while fasting for 8-12 hours and were immediately centrifuged to determine the concentration of glucose and serum fructosamine in an automated chemistry equipment. The results showed that 60% of the sampled population was male, 46.7% was 5 years old, 33.3% between 6 and 10 years old, and 20% more than 10 years old. All were consuming an exclusive diet of concentrate and all were sterilized. The results showed that 30% of canines without clinical signs of CMD presented higher glucose concentrations and fructosamine concentrations below the established biological reference interval.