Alimentary system is directly attacked by SARS-COV-2 and further prevents immune dysregulation caused by COVID-19

Abstract

Background: SARS-COV-2 causes digestive system symptom, the effect of which remains equivocal. Methods: Patients with COVID-19 were classified into four groups according to symptom. The study traced the onset and duration of symptoms, compared laboratory examinations and conducted bioinformatic analysis. Immune indices were further analysed. Results: By March 16, 25 patients with COVID-19 and 13 with suspect COVID-19 were admitted to West China Hospital, Sichuan University. Digestive system symptom group had the highest level of ESR (mm/h, P