Cell-based Immunotherapies for Cancer

Abstract

This book explores the rapidly evolving field of cancer immunotherapy, which focuses on harnessing the immune system's power to combat cancer. As traditional treatments like chemotherapy and radiation therapy often have significant side effects and may not be effective for all cancer types, immunotherapy offers a promising alternative. Among the most notable advancements in this field are cell-based therapies, which involve modifying a patient’s own immune cells or engineering specialized cells to enhance their ability to target cancer. Key approaches include chimeric antigen receptor (CAR) T-cell therapy, tumor-infiltrating lymphocyte (TIL) therapy, and dendritic cell (DC)-based therapy. Providing a comprehensive overview of these therapies, this book explores their scientific foundations, recent developments, clinical applications, and associated challenges. It also discusses emerging immunotherapeutic strategies, the commercial landscape, and future research directions. A valuable resource for researchers, clinicians, and industry professionals involved in cancer treatment, this book also serves as an informative reference for students and academics in biology, biotechnology, immunology, and related disciplines seeking a deeper understanding of cancer immunotherapy.