Investigation of efficacy of anti-aging liposomal intimate gel: An in vivo long-term study

Abstract

Liposomes have been used as universal carriers for decades, encapsulating many compounds with different cosmetic effects in order to achieve the quality, safety and efficacy of functional cosmetic products. In the present study, the efficacy of the application of the commercial liposome gel (SOPHY Anti-Aging Liposomal Intimate Gel), containing L-arginine, white curcuma extract, hyaluronic acid, lactic acid and vitamin E (previously shown to have various positive effects on the skin) as encapsulated cosmetic active ingredients, was examined in vivo on healthy volunteers. During a long-term 28-day study, biophysical skin parameters (skin humidity, TEWL, EI and pH) were monitored. As a result, an increase in skin hydration, decrease in TEWL, and a slight decrease in EI and skin pH were observed. Thus, the examined cosmetic product has shown a positive effect on skin hydration, contributing to the renewal of skin barrier, also having the anti-irritating effects.