Assessment of the effect of punch full-thickness skin grafting on wound epithelialization

Abstract

Introduction: One of the methods to accelerate skin epithelialisation is skin grafting. Various methods of skin transplantations are available, such as full thickness skin transplantation, intermediate-thickness skin transplant using a dermatome, and epidermal islet transplantation using vacuum apparatus an epidermal harvesting system. These methods, however, require the use of specialised and expensive equipment. An alternative is to perform full-thickness skin grafts with a dermatological punch. Objective: The aim of the study was to utilize the new technique of punch grafting and evaluate it's effect on wound healing. Material and methods: Five patients with granulating venous ulcers, which were not infected or cancerous, underwent the procedure. Full thickness punch grafts were placed every 2 cm2. Patients were followed up every week for 3 months and assessed for the number of micrografts rejected and percentage of the wound that has epithelialised. We have also noted the VAS pain scale. Results: Reduction in the wound area after 30 days was observed in all patients. In 2 patients, complete resolution was observed. No adverse effects were recorded. Average visual analogue scale (1-10) for pain was 4.4 ±0.927. The procedure took on average 39 ±4.3 minutes. Conclusions: Micrografts have a very high potential to accelerate the epithelialisation of chronic ulcers. Compared to the conventional procedures, they are costeffective and easier to perform. It is an effective method that can be used in outpatient settings.