Synthesis and antitumour activity of varitriol and its analogues

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Abstract

Novel analogues of (+)-varitriol have been synthesised via Julia-Kocienski olefination from γ-Dribonolactone. Newly prepared compounds were screened for their in vitro cytotoxicity towards certain human tumours and NCI 60 cancer cell line panel. © ARKAT-USA, Inc.

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Caletková, O., Lásiková, A., Hajdúch, M., Džubák, P., & Gracza, T. (2012). Synthesis and antitumour activity of varitriol and its analogues. Arkivoc, 2012(6), 365–383. https://doi.org/10.3998/ark.5550190.0013.633

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