Inhibitory effects of the constituents of hippophae rhamnoides on 3t3-l1 cell differentiation and nitric oxide production in RAW264.7 Cells

Abstract

Three new flavonol glycosides, hippophaeosides A-C (1-3), together with 27 known constituents, were isolated from Hippophae rhamnoides L. leaves. Their structures were determined by spectroscopic analyses. Their inhibitory activities on 3T3-L1 preadipocyte differentiation and triglyceride accumulation in maturing adipocytes, and nitric oxide production in RAW264.7 cells were examined. © 2013 The Pharmaceutical Society of Japan.