Photocontact Dermatitis and Contact Dermatitis from a Non-Steroidal Antiinflammatory Drug (Sector Lotion

Abstract

A 31-years-old woman applied Sector lotion® containing ketoprofen for her right ankle pain. About lOdays later, an itchy erythema developed on the applied site. Photopatch testing revealed positive reactions to Sector lotion®, ketoprofen and oxybenzone which were components of the lotion by the irradiation of UVA. Patch testing also revealed positive reactions to Sector lotion®, diisopropanolamine and polyoxyoleylether which were components of the base of the lotion. These results indicated that both photocontact dermatitis to ketoprofen and oxybenzone and contact dermatitis to the components of the base of the lotion developed at the same time. The diphenylketone structure which is common to ketoprofen and oxybenzone may be the antigenic analog of photocontact dermatitis in this case. © 1993, Meeting of Osaka Dermatological Association. All rights reserved.