The Moral Superiority of Bioengineered Wombs and Ectogenesis for Absolute Uterine Factor Infertility

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Abstract

This paper argues that uterine transplants are a potentially dangerous distraction from the development of alternative methods of providing reproductive options for women with absolute uterine factor infertility (AUFI). We consider two alternatives in particular: the bioengineering of wombs using stem cells (which would carry fewer risks than uterine transplants) and ectogenesis (which would not require surgical intervention for either the prospective mother with AUFI or a womb donor). Whether biologically or mechanically engineered, these womb replacements could provide a way for women to have children, including genetically related offspring for those who would value this possibility. Most importantly, this alternative would avoid the challenge of sourcing wombs for transplant, a practice that we argue would likely be exploitative and unethical. Continued research into bioengineering and ectogenesis will therefore remain morally important despite the recent development of uterine transplantation, even if the procedure reaches routine clinical application.

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Kendal, E., & Koplin, J. J. (2022). The Moral Superiority of Bioengineered Wombs and Ectogenesis for Absolute Uterine Factor Infertility. Cambridge Quarterly of Healthcare Ethics, 31(1), 73–82. https://doi.org/10.1017/S0963180121000827

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