A Study of Anthropometric And Lipid Profile Parameters in Non-Alcoholic Fatty Liver Disease Patients Attending A Tertiary Care Hospitalat Puducherry.

Abstract

Introduction: Non-alcoholic fatty liver disease (NAFLD)is a common chronic liver disorder sharing the same factors with metabolic syndrome in pathogenesis and insulin resistance. Stress, altered food habits and sedentary life style has led to the development of fatty liver, a marker of metabolic syndrome, leading to cardiovascular disease and Type2 DM at a younger age. Aim & objectives : To estimate anthropometric and lipid parameters in NAFLD cases, and controls with normal ultrasonogram (USG).To correlate these parameters with metabolic syndrome. Methodology : A total of 480 patients who were referred for USG from medicine and gynaecology outpatient department were screened. 46 patients with NAFLD and 46 cases with normal USG, of age 18-58 were selected as study and control group respectively. Anthropometric and lipid profile parameters were estimated in both groups. National cholesterol education programme Adult treatment panel III (NCEP-ATPIII) and International Diabetes federation Criteria was used to assess the prevalence of metabolic syndrome. Results: The WC was significantly high in the NAFLD group with a X 2 value of 25.77 and 'p' value of 0.0001. The diastolic blood pressure and serum triglycerides had X 2 value of 17.06 and 6.5 and 'p' value of 0.00003 and 0.04 respectively. Conclusion: Central obesity and dyslipidemia was significantly higher in the NAFLD group compared to the control group.