Hepatitis B Vireamia in Hepatitis B Surface Antigenemic Patients in Bangladesh

Abstract

Objectives: This study evaluates the distribution of hepatitis B vireamia in patients with hepatitis B virus (HBV) infection. Methods: HBV-infected patients were enrolled in this study. HBV DNA tests were carried out using Smart Cycler II to detect HBV DNA level in serum samples of all HBsAg-positive patients. Results: The distribution of HBV DNA level was found significantly related to age groups (p<0.05), gender group (p<0.05), ALT group (p<0.05), and HBeAg group (p<0.05). The HBV DNA level was recorded to be significantly higher in the HBeAg-positive group (p<0.05) in compared to the HBeAg-negative group. Conclusions: A low level of viral replication may persevere in chronic HBV-infected patients who are HBeAg-negative, and the level of HBV DNA was higher in the HBeAg-positive group.