Site-specific assembly of DNA-based photonic wires by using programmable polyamides

Abstract

Relay race: The first example of a programmable DNA photonic wire is reported utilizing fluorophore-tethered pyrrole-imidazole polyamides for site-directed fluorophore assembly along a pre-formed DNA duplex (see scheme; PB=Pacific Blue, Cy3=Cyanine 3; orange rectangles=fluorophore). The importance of such control is revealed by efficient energy transport over distances in excess of 27 nm. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.