A Modified Marx Generator Circuit with Enhanced Tradeoff between Voltage and Pulse Width for Electroporation Applications

Abstract

Electroporation is a next generation bioelectronics device. The emerging application of electroporation requires high voltage pulses having a pulse-width in the nanosecond range. The essential use of a capacitor results in an increase in the size of the electroporator circuit. This paper discusses the modification of a conventional Marx generator circuit to achieve the high voltage electroporation pulses with a minimal chip size of the circuit. The reduced capacitors are attributed to a reduction in the number of stages used to achieve the required voltage boost. The paper proposes the improved isolation between two capacitors with the usage of optocouplers. Parametric analysis is presented to define the tuneable range of the electroporator circuit. The output voltage of 49.4 V is achieved using the proposed 5-stage MOSFET circuit with an input voltage of 12 V.