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Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry

Science Signaling (2025) 18(887) eadw1245
DOI: 10.1126/scisignal.adw1245
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Abstract

Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography-mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendations to ensure best practices when quantifying oxylipins by LC-MS.

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Schebb, N. H., Kampschulte, N., Hagn, G., Plitzko, K., Meckelmann, S. W., Ghosh, S., … O’Donnell, V. B. (2025). Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry. Science Signaling, 18(887), eadw1245. https://doi.org/10.1126/scisignal.adw1245

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