Pertussis antibody transfer to preterm neonates after second-versus third-trimester maternal immunization

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Abstract

Preterm infants are most vulnerable to pertussis. Whether they might benefit from maternal immunization is unknown. Extending our previous results in term neonates, this observational study demonstrates that second- rather than third-trimester maternal vaccination results in higher birth anti-pertussis toxin titers in preterm neonates.

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Eberhardt, C. S., Blanchard-Rohner, G., Lemaître, B., Combescure, C., Othenin-Girard, V., Chilin, A., … Iegrist, C. A. (2017). Pertussis antibody transfer to preterm neonates after second-versus third-trimester maternal immunization. Clinical Infectious Diseases, 64(8), 1129–1132. https://doi.org/10.1093/cid/cix046

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