Baseline predictors of cognitive change in the treatment of major depressive episode: systematic review

Abstract

Background Cognitive impairment is a core feature of depression and has a negative effect on a person's functioning, in psychosocial and interpersonal areas, and on workforce performance. Cognitive impairment often persists, even with the remittance of mood symptoms. One potential way of improving treatment of cogni-tive impairment would be to identify variables that predict cognitive change in patients with depression.