Proteases A Beneficial Degradative Enzyme in Therapeutic Applications

Abstract

Proteases probably arose at the initial phases of protein development as simple degradative enzymes essential for protein degradation into its simpler form as amino acids in prokaryotic organisms. Proteases are an increasing group of enzymes that hold great potential. Proteases are produced by animals, plants, and microorganisms. Microorganisms play a dominant role in the field of proteases production. Their contribution in the life cycle of numerous pathogenic organisms has led them to become a probable target for emerging therapeutic agents in contradiction of life-threatening diseases. These enzymes are being utilized in the cure of respiratory tract issues, cardiovascular disease, inflammation, and cancer. Proteases promote healing process of tissue damage; it may be surgical or accidental damages, fractures or burns. Due to these special features, proteases are an emerging class of enzymes that possess diverse medical applications. Along with proteases, protease inhibitors are also played a very important role in disease control. Therefore protease inhibitors have drawn the attention towards their crucial role in the therapeutic application.