Abstract
A new xanthone derivative was isolated together with other 13 known constituents from a Chinese natural medicine, Swertia pseudochinensis HARA. Their structures were determined based on the spectral and chemical evidences. Furthermore, respective hexane, ethyl acetate, 1-BuOH, MeOH and water extracts of S. pseudochinensis, and purified compounds were respectively evaluated for their hepatoprotective activities against hepatocyte injury induced by CCl 4. All the extracts and isolated compounds exhibited significant hepatoprotective activities at a dose showing no hepatoxicity. © 2005 Pharmaceutical Society of Japan.
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Li, J. C., Feng, L., Sun, B. H., Ikeda, T., & Nohara, T. (2005). Hepatoprotective activity of the constituents in Swertia pseudochinensis. Biological and Pharmaceutical Bulletin, 28(3), 534–537. https://doi.org/10.1248/bpb.28.534
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