Relation between periodontitis and diabetes

Abstract

Over the last 50 years, numerous studies have been conducted to demonstrate the relationship between Periodontal Disease (PD) and Diabetes Mellitus (DM). Both these diseases share a similar pathophysiology in that they are immune related and the severity of one affects the outcomes of the other. DM and PD are both chronic diseases, which mostly affects the elderly and if left untreated can have deleterious effects on the standard of living. The exact mechanism by which DM affects the periodontium is not clear but it is thought that DM alters the harmonious oral environment making it more suitable for the growth of gram-negative bacteria. In this information on oral microbiota associated with DM, periodontal infection and systemic inflammation associated with DM, effects of DM on PD and the treatment of PD associated with DM are presented.